发明名称 Preparation for Restenosis Prevention
摘要 The invention relates to a preparation for restenosis prevention. The preparations for restenosis prevention known as yet do not reach sufficient active agent concentrations in the affected sections of the vascular walls as higher doses cause undesirable side effects. The present invention is a preparation to which at least one antihyperplastic agent is added that has a distribution ratio between butanol and water .gtoreq.0.5. The lipophilic active agent is absorbed by the vascular wall fast and in sufficient quantity. The preparation may be a liquid that can pass through capillaries and may contain a contrast agent so that the active agent is transferred into the vascular wall without any additional effort while the usually required contrast radiograms are taken. The preparation may also be applied to a catheter.
申请公布号 US2014227192(A1) 申请公布日期 2014.08.14
申请号 US201414255316 申请日期 2014.04.17
申请人 Bayer Intellectual Property Gmbh 发明人 SPECK Ulrich;SCHELLER Bruno
分类号 A61L29/08;A61K49/04;A61L29/18;A61L29/16 主分类号 A61L29/08
代理机构 代理人
主权项
地址 Monheim DE