Novel crystalline form of atorvastatin hemi-calcium salt, hydrate thereof, and method of producing the same

摘要

The present invention provides a novel crystalline form of [R-(R*,R*)]-2-(4-fluorophenyl)-²,´-dihydroxy-5-(1-mthylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof: