Detecting neoplasm from a stool sample

摘要

The present invention relates to a method of detecting cancer in a mammal, said method comprising determining whether or not a stool sample from said mammal comprises an elevated K-ras mutation score, an elevated BMP3 methylation status, and an elevated level of human DNA as compared to a normal control, wherein the presence of said elevated K-ras mutation score, said elevated BMP3 methylation status, and said elevated level of human DNA level indicates that said mammal has cancer.