发明名称 |
SIRNA TARGETING VEGFA AND METHODS FOR TREATMENT IN VIVO |
摘要 |
<p>Vascular endothelial growth factor A (VEGFA) is a chemical signal produced by cells that stimulates the growth of new blood vessels, and overexpression of VEGFA can lead to undesirable physiological conditions. Through the identification of new siRNA and modifications that improve the silencing ability of these siRNA in vivo, therapeutic compositions and methods have been invented to address the problems associated with this overexpression.</p> |
申请公布号 |
EP2598639(A4) |
申请公布日期 |
2014.08.13 |
申请号 |
EP20110813031 |
申请日期 |
2011.07.26 |
申请人 |
ALCON RESEARCH, LTD. |
发明人 |
SMITH, ANJA;REYNOLDS, ANGELA;CHATTERTON, JON, E.;ZHANG, XINYU |
分类号 |
C12N15/113;A61K31/7088 |
主分类号 |
C12N15/113 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|