SELF-ASSEMBLING POLYPEPTIDE POLYHEDRA

摘要

The invention provides a polypeptide chain capable of forming a polyhedron by self-assembly, nanostructure polyhedra self-assembled from single polypeptide chains and a process for preparing self-assembled polyhedra from polypeptide comprising coiled-coil-forming segments in defined combination that can form dimers that form the edges of the polypeptide polyhedra within a single polypeptide chain. A defined sequence of coiled-coil-forming segments allow self-assembly into a defined polyhedral nanostructure such as a polypeptide tetrahedron.