METHOD FOR THE DIRECT DETECTION AND/OR QUANTIFICATION OF AT LEAST ONE COMPOUND WITH A MOLECULAR WEIGHT OF AT LEAST 200

摘要

The present invention relates to method for the direct detection and/or quantification of at least one compound with a molecular weight of at least 200, wherein the compound to be detected and/or quantified is a chemically complex molecule, wherein said chemically complex molecule is substituted with at least two groups -R, wherein each R group means independently - OH, -OP(O)(OH) 2 or -P(O)(OH) 2 , with the proviso that at least two R are independently selected from -P(O)(OH) 2 and -OP(O)(OH) 2 , wherein the compound or compounds to be detected and/or quantified are within a biological matrix, wherein said biological matrix is a biological fluid, a biological tissue, stomach contents, intestine contents, stool sample or a culture cells, wherein the method comprises performing a chromatography and identifying the retention time and/or the intensity of the signal by means of a mass or radioactivity detector.