发明名称 |
High concentration capsaicinoid pain relief composition |
摘要 |
The present invention relates to a composition useful for pain relief. The composition is high concentration capsaicinoid topical composition comprising an analgesic agent that eliminates or reduces the burning or stinging sensation or erythema of the capsaicinoid. |
申请公布号 |
US8802736(B2) |
申请公布日期 |
2014.08.12 |
申请号 |
US201313797494 |
申请日期 |
2013.03.12 |
申请人 |
API Genesis, LLC |
发明人 |
Bucks Daniel;Birbara Philip J. |
分类号 |
A61K31/513;A61K31/045;A61K45/06;A61K9/08;A61K31/165;A61K31/125;A61K47/10;A61K31/05;A61K31/351;A61K31/352;A61K9/00;A61K31/60;A61K31/618;A61K31/35 |
主分类号 |
A61K31/513 |
代理机构 |
Nixon & Vanderhye P.C. |
代理人 |
Nixon & Vanderhye P.C. |
主权项 |
1. A liquid composition comprising:
i) 2-30% by weight of a capsaicinoid, and ii) 50-95% by weight of an analgesic agent comprising a) a topical salicylate and b) a TRPM8 agonist or a TRPV3 agonist, wherein said topical salicylate solubilizes said capsaicinoid and said TRPM8 agonist or said TRPV3 agonist, and wherein said composition comprises an amount of analgesic agent sufficient to eliminate or reduce the burning or stinging sensation or erythema created by the topical administration of the capsaicinoid to a mammal. |
地址 |
Fairfax VA US |