Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution

摘要

Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function. The first transfer function can be at least partially different from the second transfer function. The data can be generated based on the second and fourth radiations.

主权项

1. A method for generating data associated with at least one portion of an anatomical sample, comprising:
forwarding at least one first radiation at to the at least one portion through at least one optical arrangement, and receiving at least one second radiation from the at least one portion within the anatomical sample which is based on the at least one first radiation, wherein, based on an interaction between the at least one optical arrangement and at least one of the first radiation or the second radiation, the at least one optical arrangement has a first transfer function; forwarding at least one third radiation to the at least one portion through the at least one optical arrangement, and receiving at least one fourth radiation from the at least one portion within the anatomical sample which is based on the at least one third radiation, wherein, based on an interaction between the at least one optical arrangement and at least one of the third radiation or the fourth radiation, the at least one optical arrangement has a second transfer function, and wherein the first transfer function is at least partially different from the second transfer function; and generating the data based on the separated second and fourth radiations.