发明名称 Cobalamin assay
摘要 The present invention provides a specific binding partner for holoTC having a specificity for holoTC over apoTC of at least 40-fold and an assay method for assaying for holoTC in a sample, the method comprising contacting the sample with a specific binding partner for holoTC and detecting the resultant conjugates.
申请公布号 US8802382(B2) 申请公布日期 2014.08.12
申请号 US201314138217 申请日期 2013.12.23
申请人 Axis-Shield ASA 发明人 Orning Lars;Rian Anne
分类号 G01N31/00;G01N33/53 主分类号 G01N31/00
代理机构 Bacon & Thomas, PLLC 代理人 Bacon & Thomas, PLLC
主权项 1. An assay method for assaying for holoTC in a sample, said method comprising contacting said sample with a specific binding partner for holoTC and detecting the resultant conjugates of holoTC and the specific binding partner, wherein: said specific binding partner is a specific binding partner for holoTC having a specificity for holoTC over apoTC of at least 40-fold, and said specific binding partner also has affinity for at least one constrained peptide comprising the motif SFFYSLCYCW (SEQ ID NO: 9), relative to apoTC of at least 40-fold.
地址 Oslo NO