发明名称 | Cobalamin assay | ||
摘要 | The present invention provides a specific binding partner for holoTC having a specificity for holoTC over apoTC of at least 40-fold and an assay method for assaying for holoTC in a sample, the method comprising contacting the sample with a specific binding partner for holoTC and detecting the resultant conjugates. | ||
申请公布号 | US8802382(B2) | 申请公布日期 | 2014.08.12 |
申请号 | US201314138217 | 申请日期 | 2013.12.23 |
申请人 | Axis-Shield ASA | 发明人 | Orning Lars;Rian Anne |
分类号 | G01N31/00;G01N33/53 | 主分类号 | G01N31/00 |
代理机构 | Bacon & Thomas, PLLC | 代理人 | Bacon & Thomas, PLLC |
主权项 | 1. An assay method for assaying for holoTC in a sample, said method comprising contacting said sample with a specific binding partner for holoTC and detecting the resultant conjugates of holoTC and the specific binding partner, wherein: said specific binding partner is a specific binding partner for holoTC having a specificity for holoTC over apoTC of at least 40-fold, and said specific binding partner also has affinity for at least one constrained peptide comprising the motif SFFYSLCYCW (SEQ ID NO: 9), relative to apoTC of at least 40-fold. | ||
地址 | Oslo NO |