AMPHIPHILIC BLOCK COPOLYMERS OF N-DERIVATIVES OF NATURAL BIBASIC AMINO ACIDS AND POLYETHER GLYCOLS

摘要

The invention relates to the preparation of novel dispersions for transport of medicinal preparations in living body, for use in cosmetic, pharmaceutical agents and bioactive additives.Disclosed are amphiphilic block copolymers of N-derivatives of natural bibasic amino acids and polyether glycols of general formula:,.The technical result is in that synthesized block copolymers act as surfactants due to regular alternation of lipophilic hydrophilic blocks in macromolecule, reduce air-water interfacial tension and solubilize water-insoluble matters. Labile ester link of separate blocks in block copolymers provides biodegradability, and building block structure provides easy metabolism and excretion.