COMPOSITION FOR USE IN PREVENTION OR TREATMENT OF MISCARRIAGE, PRE-ECLAMPSIA, AND IMMATURE FETUS, COMPRISING PECAM-1 ACTIVATING CATALYST AS ACTIVE INGREDIENT

摘要

The present invention relates to a composition for use in the prevention or treatment of miscarriage, pre-eclampsia, and an immature fetus, comprising a PECAM-1 activating catalyst as an active ingredient. The PECAM-1 activating catalyst according to the present invention increases regulatory T cells (Treg) in the mother, and markedly decreases miscarriage when animal models of miscarriage are treated with sCD38; thus, the catalyst can be useful as a prophylactic or therapeutic agent for miscarriage, pre-eclampsia, and an immature fetus.