| 主权项 |
1. A cartilage composition for repairing articular cartilage defects comprises:
an articular cartilage material, the material being non-demineralized and not subjected to demineralization treatments or harsh chemicals which alter the natural properties of the cartilage material, the cartilage material in the form of pieces of cartilage having been washed in normal saline washes and frozen rapidly, not having been subjected to elevated temperatures greater than 50 degrees C. is dried to about 3 to 5 percent moisture content, the pieces of cartilage material being preserved, freeze-dried, frozen or cryo-preserved cartilage; the pieces of preserved cartilage material is ground or milled or shaved intermittently without raising the temperature above 40 degrees C. to form a ground, milled or shaved material of a cartilage fluff and cartilage particles, after each grinding or milling cycle, the material is sieved through sieve openings of 850 μm and 1000 μm size allowing the cartilage particles to pass and a cartilage fluff made of a plurality of branched strands to be separated from the particles, the cartilage fluff having cohesive characteristics wherein the fluff sticks to itself to form a continuous network of cartilage fluff for packing into defects of articular cartilage or bone. |
