发明名称 |
ADMINISTRATION OF AN ANTI-ACTIVIN-A COMPOUND TO A SUBJECT |
摘要 |
The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor. In some embodiments, at least two compounds are administered to the subject, where the first compound is an anti-activin A compound, and the second compound is a chemotherapeutic compound, for example capecitabine.The invention further relates to methods of identifying subjects for treatment factors. |
申请公布号 |
WO2014121221(A1) |
申请公布日期 |
2014.08.07 |
申请号 |
WO2014US14490 |
申请日期 |
2014.02.03 |
申请人 |
SANTA MARIA BIOTHERAPEUTICS, INC.;AMGEN INC. |
发明人 |
HAN, HUIQUAN;HAQQ, CHARISTOPHER, MICHAEL;CIECHANOVER, ISAAC;ZHOU, XIAOLAN;LU, JOHN, ZHAO-NIAN |
分类号 |
C07K16/26;A61K31/395;C07K16/00 |
主分类号 |
C07K16/26 |
代理机构 |
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