Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands

摘要

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.;

主权项

1. A compound of formula I, or a stereoisomer thereof,wherein R1 is pyrrolotriazinyl substituted with 1 halo substituent; or a pharmaceutically acceptable salt thereof.