Method and Implantable System for Blood-Glucose Concentration Monitoring Using Parallel Methodologies

摘要

In an implantable medical device for monitoring glucose concentration in the blood, a blood-glucose concentration analysis is performed using correlations of blood-glucose concentration with measures of metabolic oxygen consumption including oxymetric, and/or temperature. Analysis of electrocardiographic data is used in a parallel method to detect and/or confirm the onset and/or existence and/or extent of hypoglycemia and/or hyperglycemia. Blood-glucose concentration calculation is enhanced by using the combination of the oxygen metabolism analysis and electrocardiographic analysis.

主权项

1. An implantable system for monitoring blood-glucose concentration in a patient, comprising:
an EGM sensing circuit that senses one or more cardiac electrical signal and generates EGM data indicative of the one or more cardiac electrical signal; an EGM analysis unit that receives the EGM data from the EGM sensing circuit and generates a first metric of blood-glucose concentration using the EGM data; an oxygen metabolism sensor that monitors one or more property of oxygen metabolism and generates oxygen metabolism data indicative of the one or more property of oxygen metabolism; an oxygen metabolism analysis unit that receives the oxygen metabolism data from the oxygen metabolism sensor and generates a second metric of blood-glucose concentration using the oxygen metabolism data; and a blood-glucose concentration analysis unit that receives the first metric of blood-glucose concentration and the second metric of blood-glucose concentration and generates an enhanced metric of blood-glucose concentration.