| 摘要 |
The invention provides agents and compounds which can be used to modulate the activity of the complement system. The invention provides novel biological targets associated with such modulation, and also pharmaceutical compositions, medicaments and methods of treatment for use in preventing, ameliorating or treating diseases that are characterised by inappropriate complement activity, for example age-related macular degeneration (AMD), meningitis, renal disease, autoimmune disease or inflammation. The invention also extends to therapeutic antibodies, and to screening assays for identifying agents useful in treating these diseases. |
