Method and Formulation for Chemical Peeling

摘要

A chemical peeling formulation and a formulation able to increase the efficacy and the tolerability of preparations based on the use of compounds used to carry out chemical peeling, comprising at least one keratolytic agent and dimethyl isosorbide. The composition may additionally comprise dimethyl sulphone.

主权项

1. A method for chemical peeling, comprising applying to the skin a composition comprising at least one keratolytic agent and dimethyl isosorbide, wherein
said keratolytic agent has a pKa in the range 2.0-3.0 and said composition has a specific conductivity in the range 0.005-40 mS cm−1 wherein said chemical peeling to be obtained is at superficial levels of the skin structure; said keratolytic agent has a pKa equal or above 3 and said composition has a specific conductivity in the range 1.6-6 mS cm−1 wherein said chemical peeling to be obtained is at average levels of the skin structure; said keratolytic agent has a pKa in the range 0.5-2.0 and said composition has a specific conductivity in the range 40-250 mS cm−1 wherein said chemical peeling to be obtained is at deep levels of the skin structure.