Compositions and Methods for Treating Skeletal Myopathy

摘要

The present invention provides a method of preventing or treating a myopathy, such as a skeletal myopathy, comprising administering a modulator of a miRNA. In one embodiment, the skeletal myopathy is centronuclear myopathy. The modulator can be an agonist that promotes the expression, function or activity of a miR-133 family member. The miR-133 family member can be miR-133a or miR-133b.

主权项

1. A method of preventing or treating a centronuclear myopathy in a subject in need thereof comprising administering to the subject an agonist of a miR-133 family member.