| 发明名称 |
DISEASE CONTROL WITH TICK PHOSPHOLIPASE A2 |
| 摘要 |
The present invention relates to reagents and methods for the modulation of viability of bacteria. A process is provided wherein a protein sequence from A. americanum saliva effective in reducing the viability of gram positive, gram negative, or acid-fast bacteria and spirochetes including B. burgdurferi is administered. The inventive protein from A. americanum saliva has utility as a therapeutic for the treatment of an organism infected with bacteria, particularly the spirochete B. burgdorferi. |
| 申请公布号 |
US2014219985(A1) |
申请公布日期 |
2014.08.07 |
| 申请号 |
US201414249503 |
申请日期 |
2014.04.10 |
| 申请人 |
The United States of America,as represented by the Secretary,Department of Health and Human Services |
发明人 |
Zeidner Nordin;Dolan Marc;Champagne Donald |
| 分类号 |
A01N37/46;A61K38/46 |
主分类号 |
A01N37/46 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process of altering the viability of a bacterial organism comprising:
contacting a bacterial organism with a salivary protein derived from A. americanum wherein said protein has phospholipase A2-like activity. |
| 地址 |
Atlanta GA US |
