<p>A chimeric endonuclease is provided comprising the GIY-YIG nuclease domain which is linked to a DNA-targeting domain by a linking domain. The endonuclease is useful in gene editing.</p>
申请公布号
WO2014121222(A1)
申请公布日期
2014.08.07
申请号
WO2014US14491
申请日期
2014.02.03
申请人
THE UNIVERSITY OF WESTERN ONTARIO;EDGELL, DAVID R.;KLEINSTIVER, BENJAMIN P.;WANG, LI;BOGDANOVE, ADAM J.
发明人
EDGELL, DAVID R.;KLEINSTIVER, BENJAMIN P.;WANG, LI;BOGDANOVE, ADAM J.
