| 发明名称 |
Method and Medicament for Inhibiting the Expression of a Given Gene |
| 摘要 |
The invention relates to an isolated RNA that mediates RNA interference of an mRNA to which it corresponds and a method of mediating RNA interference of mRNA of a gene in a cell or organism using the isolated RNA. |
| 申请公布号 |
US2014220676(A1) |
申请公布日期 |
2014.08.07 |
| 申请号 |
US201414218489 |
申请日期 |
2014.03.18 |
| 申请人 |
Alnylam Pharmaceuticals, Inc. |
发明人 |
Kreutzer Roland;Limmer Stefan |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An oligoribonucleotide of double-stranded structure (dsRNA) for inhibiting the expression of a given target gene in mammalian cells, wherein the dsRNA has 21 to 49 base pairs and has a complementary region I that is incorporated in the dsRNA. |
| 地址 |
Cambridge MA US |
