METHODS OF CONTROLLING VASCULARITY USING RAVER2 AS A MEDIATOR FOR EXPRESSION OF VEGF RECEPTOR SFIT1

摘要

Methods of treating a condition in a subject resulting from abnormally high VEGF signaling through membrane-bound receptors. Such a method can include increasing expression of Raver2 in affected cells of the subject to increase production of soluble VEGF receptors. In some aspects, increasing expression of Raver2 decreases production of membrane-bound VEGF receptors.