发明名称 |
ULTRASENSITIVE DETECTION OF BETA HEMOLYTIC STREPTOCOCCUS |
摘要 |
The present invention is directed to a method for the ultrasensitive detection of beta hemolytic Streptococcus, a bacterium implicated in strep throat, using a specific protease marker. Also disclosed is a device as well as a biosensor, both of which are useful for the detection of beta hemolytic Streptococcus. The biosensor and the device can be used in conjunction with other reagents as part of a kit for detecting strep throat. |
申请公布号 |
US2014220589(A1) |
申请公布日期 |
2014.08.07 |
申请号 |
US201113825076 |
申请日期 |
2011.09.22 |
申请人 |
Sanders Mitchell C.;Macy Dale;Rakitin Andrei |
发明人 |
Sanders Mitchell C.;Macy Dale;Rakitin Andrei |
分类号 |
G01N33/569 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
1. A device for detecting the presence or absence of a bacterium in a sample, comprising a first amplifier configured to release a substrate in response to an enzyme initiated by the bacterium; and a second amplifier, in fluid communication with the first amplifier, configured to bind to the released substrate and to produce a signal in the presence of the bacterium. |
地址 |
Northborough MA US |