APPLICATION OF MICRORNA OR INHIBITOR THEREOF IN LIPID METABOLISM REGULATION AND CONTROL

摘要

The present invention provides an application of a microRNA or an inhibitor thereof, and specifically, the present invention provides an application of the microRNA or the inhibitor in preparing a medicine for regulating lipid metabolism or preparing a medicine for preventing or treating a disease related to lipid metabolism. The microRNA comprises one or more of the following: miRNA-96, miRNA-185, and miRNA-223. The present invention also provides an application of the microRNA or the inhibitor thereof in regulating a protein expression level related to lipid metabolism. The present invention also provides a composition comprising the microRNA or the inhibitor thereof. The microRNA or the inhibitor thereof in the present invention can be used as a pharmaceutical component, and can be applied in preventing or treating diseases related to hyperlipidemia, atherosclerosis, coronary heart disease or other diseases caused by lipid metabolism disorders.