PYRIDOPYRIMIDINE BASED DERIVATIVES AS POTENTIAL PHOSPHODIESTERASE 3 (PDE3) INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF

摘要

The present invention provides compounds of formula 1 as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.;Where in
X=H, alkyl, aryl, heteroarylY=H, alkyl, aryl, heteroarylR=substituted phenyl;A=H, alkyl, alkoxy, halo, dihaloB=H, alkyl, alkoxy, halo, dihaloC=H, alkyl, alkoxy, halo, dihalo

主权项

1. A compound having formula 1.Where in
X=H, alkyl, aryl, heteroaryl Y=H, alkyl, aryl, heteroaryl R=substituted phenyl A=H, alkyl, alkoxy, halo, dihalo B=H, alkyl, alkoxy, halo, dihalo C=H, alkyl, alkoxy, halo, dihalo