发明名称 A BIOMARKER ALGORITHM FOR DETERMINING THE TIME OF STROKE SYMPTOM ONSET AND METHOD
摘要 A method of determining the time of stroke symptom onset is provided including obtaining a biological sample from an individual; contacting the biological sample with a detection composition comprising at least one expression mediator of a LY96, ARG1, CA4, and a TLR expression mediators, or a combination of these expression mediators, wherein at least one of the expression mediators is associated with an acute phase response of ischemic stroke, for forming a detectable response; and correlating the detectable response with a time of onset of one or more stroke symptoms. A composition is provided having a nucleic acid probe, an antibody, or a purified biomarker that is specific for at least one of a LY96, ARG1, CA4, and TLR expression mediators, or a combination of these expression mediators.
申请公布号 WO2014120731(A1) 申请公布日期 2014.08.07
申请号 WO2014US13543 申请日期 2014.01.29
申请人 WEST VIRGINIA UNIVERSITY 发明人 BARR, TAURA L.
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
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