| 发明名称 |
PEPTIDE DEFORMYLASE INHIBITORS |
| 摘要 |
The present invention relates to {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide compounds of Formula (I): or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity and in treatment methods for bacterial infections. |
| 申请公布号 |
KR20140097518(A) |
申请公布日期 |
2014.08.06 |
| 申请号 |
KR20147017934 |
申请日期 |
2012.11.30 |
| 申请人 |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED |
发明人 |
AUBART KELLY MARSHALL;GILLIAN JASON MICHAEL;QIN DONGHUI;MCKEOWN ROBERT RAHN;WILLIAMS GLENN R. |
| 分类号 |
C07D413/04;A61K31/4985;C07D239/24;C07D498/04 |
主分类号 |
C07D413/04 |
| 代理机构 |
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