发明名称 |
IMMEDIATE RELEASE COMPOSITIONS OF ACID LABILE DRUGS |
摘要 |
The present invention provides a method of creating a macro environment in the stomach for immediate release of acid labile compounds stable at alkaline or near alkaline pH comprising the step of administering a composition comprising acid labile compound stable at alkaline or near alkaline pH together with a water soluble buffer, a water insoluble buffer, a disintegrant and pharmaceutically acceptable excipients. The present invention also provides a pharmaceutical composition of a multi component system in which one component essentially contains an acid labile drug and the other component comprises a fast releasing buffer composition along with pharmaceutically acceptable excipients for oral administration and ingestion by a subject, and process for preparing the same. |
申请公布号 |
EP2523654(A4) |
申请公布日期 |
2014.08.06 |
申请号 |
EP20110731713 |
申请日期 |
2011.01.07 |
申请人 |
MOHAMED SHAFEE, MUNEERA;KANDASAMY, RUCKMANI;KONDAGULI, ANAND VASANTHARAO |
发明人 |
OMAR ABDULGANI, THUSLEEM;SHAIKH, SALEEM, ZAINUDDIN |
分类号 |
A61K9/28;A61K9/20;A61K9/48;A61K31/4439;A61K47/02 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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