LABELLED MODIFIED GUANINE-CONTAINING NUCLEOSIDES AND NUCLEOTIDES COMPRISING A FLUOROPHORE ATTACHED TO THE BASE THROUGH A LINKING GROUP COMPRISING A POLYETHYLENE GLYCOL SPACING GROUP AND METHODS FOR THEIR USE

摘要

The invention is directed to modified guanine-containing nucleosides and nucleotides and uses thereof. More specifically, the invention relates to modified fluorescently labelled guanine-containing nucleosides and nucleotides which exhibit enhanced fluorophore intensity by virtue of reduced quenching effects.