发明名称 Method for the selection of antibodies against BCMA
摘要 <p>An antibody specifically binding to human BCMA, characterized in that the binding of said antibody is not reduced by APRIL and not reduced by BAFF, said antibody does not alter APRIL-dependent NF-ºB activation, BAFF-dependent NF-ºB activation, and does not alter NF-ºB activation without BAFF and APRIL is useful as a therapeutic agent.</p>
申请公布号 EP2762496(A1) 申请公布日期 2014.08.06
申请号 EP20130000570 申请日期 2013.02.05
申请人 ENGMAB AG 发明人 VU, MINH DIEM;STREIN, KLAUS
分类号 C07K16/28;A61P31/00 主分类号 C07K16/28
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