1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE

摘要

The present invention provides a compound represented by the following general formula (I) or a salt thereof which has a Syk inhibitory effect (in the formula R 1 represents a hydrogen atom or an optionally R a -substituted C 1 -C 6 alkyl group; A represents a hydrogen atom, an optionally R a -substituted C 1 -C 8 alkyl group, an optionally R a -substituted C 2 -C 6 alkenyl group, an optionally R a -substituted C 2 -C 6 alkynyl group, an optionally R b -substituted C 3 -C 10 cycloalkyl group, an optionally R b -substituted C 6 -C 14 aromatic hydrocarbon group, an optionally R b -substituted 4- to 10-membered unsaturated heterocyclic group, or an optionally R b -substituted 4-to 10-membered saturated heterocyclic group, or optionally forms a 4- to 10-membered unsaturated heterocyclic ring or a 4- to 10-membered saturated heterocyclic ring together with R 1 and the nitrogen atom bonded thereto; R 2 represents a hydrogen atom or an optionally R a -substituted C 1 -C 6 alkyl group; and B represents an optionally R c -substituted unsaturated heterocyclic group).