Apparatus and method for the ligation of tissue

摘要

A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.

主权项

1. A system for facilitating ligation of a left atrial appendage comprising:
an intrapericardial device comprising: an elongate body having a proximal end, a distal end, and a lumen therethrough, wherein the elongate body has a diameter of approximately 24 French or smaller; a first guide member advanceable through the elongate body, and comprising a first magnetic element at a distal end of the first guide member, the first magnetic element placed outside the left atrial appendage to couple with a counterpart magnetic element placed inside of the left atrial appendage; and a first expandable member slidably disposed within the distal end of the elongate body, wherein the expandable member is capable of encircling the left atrial appendage; and a trans-septal device comprising: a second guide member comprising the counterpart magnetic element; and a second expandable member sized and configured to expand inside the left atrial appendage, wherein the counterpart magnetic element is distal to the second expandable member.