Functional near-infrared spectroscopy as a monitor for depth of anesthesia

摘要

Disclosed are methods and devices for measuring a state of anesthesia in a noninvasive manner. Optical techniques may be used to measure changes in a functional near-infrared (fNIR) signal, where the fNIR signal is received in response to directing wavelengths of light in a near-infrared range on a patient. The optical density change may be used to obtain a change in deoxyhemoglobin (deoxy-Hb) concentration and/or a change in an oxyhemoglobin concentration (oxy-Hb). The changes in the deoxy-Hb and/or the oxy-Hb may then be compared to determine a state of anesthesia.;The effect of artifacts (e.g., strong surgery room lighting, patient-table tilting, patient intubation/extubation) on the fNIR signal may be removed using a noise removal algorithm. In selecting the noise removal algorithm, a switching technique may be used to select the component analysis algorithm, such as a principal component analysis (PCA), an independent component analysis (ICA), or the like.

主权项

1. A method comprising:
receiving a near-infrared signal in response to directing wavelengths of light in a near-infrared range on a patient; determining, from the near-infrared signal, a relative deoxyhemoglobin concentration and oxyhemoglobin concentration; analyzing the percentage of the deoxyhemoglobin concentration to determine a corresponding state of anesthesia; and administering an amount of anesthetic according to the corresponding state of anesthesia.