| 发明名称 | Therapeutic or prophylactic agent for dyskinesia | ||
| 摘要 | An object of the present invention is to provide a drug with a high therapeutic or prophylactic effect on dyskinesia, without accompanying aggravation of symptoms of the primary disease, and with fewer side effects.;Accordingly, the present invention provides a therapeutic or prophylactic agent for dyskinesia, comprising as an effective component a compound having a 4,5-epoxy morphinan skeleton, which compound is represented by the Formula (I) below, or a pharmaceutically acceptable acid addition salt thereof:; [wherein the double line composed of a dashed line and a solid line represents a double bond or single bond, R1 is C4-C7 cycloalkylalkyl, R2 is C1-C5 straight or branched alkyl, and B is —CH═CH—.] | ||
| 申请公布号 | US8796301(B2) | 申请公布日期 | 2014.08.05 |
| 申请号 | US200812597442 | 申请日期 | 2008.04.24 |
| 申请人 | Toray Industries, Inc. | 发明人 | Ikeda Ken;Mochizuki Hidenori |
| 分类号 | A01N43/42;A61K31/44;C07D489/00 | 主分类号 | A01N43/42 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A method for treating dyskinesia, comprising administrating an effective amount of a compound represented by the Formula (I) below or a pharmaceutically acceptable acid addition salt thereof to a patient in need of treatment of dyskinesia:wherein the double line composed of a dashed line and a solid line represents a double bond or a single bond, R1 is C4-C7 cycloalkylalkyl, R2 is C1-C5 straight or branched alkyl, and B is —CH═CH—. | ||
| 地址 | Tokyo JP | ||