摘要 |
The present application describes fusion proteins that includes coiled coil domain capable of forming dimers or multimers, in particular that coiled coil domain from GCN4, cartilage matrix protein, cartilage oligomeric matrix protein or matrilin, fused to a further domain, in particular those derived from angiopoietin, an ephrin, thrombospondin, VEGF, EGF, PDGF, FGF, NGF, erythropoietin, an interleukin or RANKL. |