| 发明名称 | Erk1/2 posphorylation site specific antibody | ||
| 摘要 | The invention relates to an antibody specific to Erk1/2 phosphorylated at Thr188 and a method for producing the same. The invention also relates to an in vitro method for determining the presence of phosphorylated Erk1/2 in a sample using the antibody of the invention. Therefore, the invention also comprises an assay for diagnosing a heart disease in vitro comprising the antibody of the invention and certain uses of the antibody. Moreover the invention relates to a peptide used to produce the antibody. | ||
| 申请公布号 | US8796428(B2) | 申请公布日期 | 2014.08.05 |
| 申请号 | US200913130495 | 申请日期 | 2009.11.26 |
| 申请人 | Julius-Maximilians-Universitaet Wuerzburg | 发明人 | Lohse Martin J.;Lorenz Kristina |
| 分类号 | C07K16/40;C07K16/00;C12N5/07;G01N33/53 | 主分类号 | C07K16/40 |
| 代理机构 | Smith, Gambrell & Russell, LLP | 代理人 | Sundby, Esq. Suzannah K.;Smith, Gambrell & Russell, LLP |
| 主权项 | 1. A purified phospho-specific antibody for Erk1/2 raised against a peptide consisting of SEQ ID NO: 1 wherein the Thr at position 8 of the sequence is phosphorylated, said antibody is specific to the peptide and does not cross-react with Erk phosphorylated at Thr183/Thr185. | ||
| 地址 | Wuerzburg DE | ||