| 发明名称 | Inhibitors of guanine exchange factors and their use as anticancer drugs | ||
| 摘要 | A peptide including the amino acids sequence X9CGYX13X14AX16X17X18MX20X21X22X23X24X25X26X27CPLCX32X33, a nucleic acid coding for the peptide, and/or a recombinant vector including the nucleic acid for the preparation of a drug intended for the treatment of cancer. | ||
| 申请公布号 | US8796415(B2) | 申请公布日期 | 2014.08.05 |
| 申请号 | US200913503092 | 申请日期 | 2009.10.22 |
| 申请人 | Centre National de la Recherche Scientifique;Universite Montpellier 2—Sciences et Techniques | 发明人 | Debant Anne;Schmidt Susanne;Bouquier Nathalie;Fromont Sylvie |
| 分类号 | A61K38/00 | 主分类号 | A61K38/00 |
| 代理机构 | Young and Thompson | 代理人 | Young and Thompson |
| 主权项 | 1. A method for treating cancer, comprising administering to a subject in need thereof a therapeutically effective amount of an isolated peptide comprising the amino acid sequence SEQ ID NO: 3ICGYX13LAX16X17X18MLGPX23X24RVX27CPLCX32P wherein X13, X16, X17, X18, X23, X24, X27 and X32 represent any amino acids, and having at least one of the following features: X13 is D; X16 is M or A; X17 is S; X18 is D, G or A; X23 is G; X24 is A; X27 is L; and X32 is G. | ||
| 地址 | Paris FR | ||