发明名称 CYCLOPALLADATED COMPOUNDS COMPRISING BIS-DIPHENYLPHOSPHINE-FERROCENE LIGANDS, AND THEIR USE IN TREATING DISEASES
摘要 The invention relates to cyclopalladated compounds containing bis-diphenylphosphine-ferrocene ligands and their analogues which are active inhibitors of proteins and enzymes, for example, those of the serine peptidase, cysteine-protease, metalo-protease and endopeptidase families, involved in the development and metastases of malignant tumors, e.g. of the thyroid. An exemplary compound is shown in the figure. The compounds are able te modulate the immunological system due to their action on the enzymes and their interaction with DNA molecules.
申请公布号 CA2496681(C) 申请公布日期 2014.08.05
申请号 CA20032496681 申请日期 2003.08.22
申请人 FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO-FAPESP 发明人 CAIRES, ANTONIO CARLOS FAVERO;TRINDADE, CLAUDIA BINCOLETTO;TERSARIOL, IVARNE LUIS DOS SANTOS
分类号 C07F17/02;A61K31/28;A61K31/555;C07F15/00 主分类号 C07F17/02
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