发明名称 ISOXAZOLE COMBRETASTIN DERIVATIVES FOR THE TREATMENT OF DISORDERS
摘要 <p>The invention relates to compounds of structural formula (I); or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.</p>
申请公布号 CA2597430(C) 申请公布日期 2014.08.05
申请号 CA20062597430 申请日期 2006.02.16
申请人 SYNTA PHARMACEUTICALS CORP. 发明人 SUN, LIJUN;BORELLA, CHRISTOPHER;LI, HAO;JIANG, JUN;CHEN, SHOUJUN;KOYA, KEIZO;INOUE, TAKAYO;DU, ZHENJIAN;FOLEY, KEVIN;WU, YAMING;ZHANG, MEI;YING, WEIWEN
分类号 C07D261/08;A61K31/42;A61P35/00;C07D413/04 主分类号 C07D261/08
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