Medical devices having fluorine-containing polymer coatings with improved adhesion

摘要

According to an aspect of the present invention, medical devices are provided which include a metallic substrate and a polymeric region disposed over and in contact with the metallic substrate. The polymeric region includes (a) a fluorine-containing polymer that contains at least one type of fluorine-containing monomer selected from a vinylidene fluoride monomer, a hexafluoropropylene monomer, and a combination thereof, and (b) an adhesion promoting copolymer that contains (i) at least one type of first monomer that covalently or non-covalently bonds with the metallic substrate and (ii) at least one type of second monomer selected from acrylate monomers, methacrylate monomers, fluorine-containing monomers, and combinations thereof.

主权项

1. A medical device comprising: a metallic substrate and a polymeric region disposed over and in contact with the metallic substrate, said polymeric region comprising (1) a fluorine-containing polymer which is a random copolymer of vinylidene fluoride and hexafluoropropylene and (2) an adhesion promoting copolymer that comprises (i) a first monomer which is an acidic monomer that non-covalently bonds with the metallic substrate and (ii) n-butyl acrylate as a second monomer.