Device for intermittently obstructing a gastric opening and method of use

摘要

The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.

主权项

1. An obstructing member for intermittently obstructing a pyloric valve, comprising:
an occluding member having a low-profile configuration for trans-luminal delivery into a patient's stomach and a deployment configuration having a wider shape relative to the low-profile configuration, wherein the occluding member comprises an elongate structure extended longitudinally in the low-profile configuration; a locking mechanism coupled with the occluding member; a flexible tether having a length with a proximal end attached to the occluding member; and, a distal member attached to a distal end of the flexible tether and having an atraumatic shape, wherein the elongate structure forms a coiled or wound structure defining a plurality of turns which nest one adjacent to the other assuming a compact shape in the deployment configuration and whereby the occluding member encloses the locking mechanism and the occluding member is locked into its deployment configuration such that passage through the pyloric valve is inhibited or prevented by the obstructing member and where the obstructing member is further configured to intermittently contact and obstruct the pyloric valve.