发明名称 PROLYL HYDROXYLASE INHIBITORS
摘要 <p>PROBLEM TO BE SOLVED: To provide a pharmaceutical composition comprising a useful compound or a pharmaceutically acceptable salt thereof to various infectious diseases which inhibits a prolyl hydroxylase in order to stabilize hypoxia inducible factor (HIF)-1αand HIF-2α.SOLUTION: A compound having the formula: where Z is phenyl substituted with from 1 to 5 halogens chosen from F and Cl; Ris C-Clinear alkyl or C-Cbranched alkyl; and which is effective against diseases caused by pathogens selected from bacteria, viruses, yeast, fungi, or parasites.</p>
申请公布号 JP2014139206(A) 申请公布日期 2014.07.31
申请号 JP20140045734 申请日期 2014.03.07
申请人 AERPIO THERAPEUTICS INC 发明人 JOSEPH H GARDNER;ROBERT SHALWITZ
分类号 A61K31/496;A61P17/00;A61P17/02;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P33/00;A61P37/04;A61P43/00;C07D213/69 主分类号 A61K31/496
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