摘要 |
PROBLEM TO BE SOLVED: To provide compounds having activity as serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors to treat chronic pain, such as neuropathic pain.SOLUTION: The invention relates to compounds represented by formula I, where a is 0-4; Ris independently halo or trifluoromethyl; Ris H, halogen, or alkyl; and Rare independently H, or halogen. |