| 发明名称 |
PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION |
| 摘要 |
Survival of, or axon regeneration in a lesioned mature central nervous system (CNS) neuron is promoted by (a) contacting the neuron with a therapeutically effective amount of an exogenous activator of protein translation; and (b) detecting the resultant promotion of the survival of, or axon regeneration in the neuron. |
| 申请公布号 |
US2014213609(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
US201414244065 |
申请日期 |
2014.04.03 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
HE Zhigang;PARK Kevin;LIU Kai;HU Yang |
| 分类号 |
A61K31/4745 |
主分类号 |
A61K31/4745 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for promoting survival of, or axon regeneration in a lesioned mature neuron in situ, comprising contacting the lesioned neuron with a therapeutically effective amount of a PTEN inhibitor, to thereby promote survival of, or axon regeneration in the neuron. |
| 地址 |
Boston MA US |
