METHODS FOR CLEANING AND STERILIZATION OF IMPLANT TISSUE EX VIVO WITH SHOCK WAVES

摘要

This invention includes methods for cleaning and sterilizing tissue harvested for implant with shock waves by submerging the harvested tissue in a volume of fluid in a holding vessel including a shock wave applicator with a focal volume in the volume of fluid, and applying a pressure shock wave pulses to the harvested tissue from the shock wave applicator in sufficient amounts to eliminate biological contaminants in the harvested tissue.

主权项

1. A method comprising;
providing a volume of fluid in a holding vessel, wherein the holding vessel includes a shock wave applicator configured to have a focal volume disposed in the volume of fluid; submerging at least a portion of a harvested tissue including biological contaminants into the volume of fluid; and applying a plurality of pressure shock wave pulses, by the shock wave applicator, to the at least a portion of harvested tissue in the volume of fluid in sufficient amounts to damage at least some of biological contaminants in the harvested tissue.