<p>The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.</p>
申请公布号
WO2014114532(A1)
申请公布日期
2014.07.31
申请号
WO2014EP50645
申请日期
2014.01.15
申请人
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC.;SIENA BIOTECH S.P.A.;WOLTERING, THOMAS
发明人
WOLTERING, THOMAS;GUBA, WOLFGANG;HILPERT, HANS;KUGLSTATTER, ANDREAS;LIMBERG, ANJA;OBST SANDER, ULRIKE;PINARD, EMMANUEL;WOSTL, WOLFGANG