RECOMBINANT SALMONELLA SUPPRESSING THYMUS AND ACTIVATION-REGULATED CHEMOKINE FOR TREATMENT OF ASTHMA AND COMPOSITION OF THERAPEUTIC AGENT COMPRISING THE SAME

摘要

The present invention relates to a composition for treating asthma, wherein the composition contains a bacterial cell as an active ingredient, and the bacterial cell is transformed by a recombinant vector which expresses small interfering RNA (siRNA) which controls the expression of thymus and activation-regulated chemokine genes. According to the present invention, the expression of the thymus and activation-regulated chemokine genes is controlled so that the expression of ROS and the hypersensitivity of airway are alleviated and asthma which has been intractable and did not have appropriate treating agents can be treated.