| 发明名称 |
METHOD AND COMPOSITION FOR TREATING SPASTICITY |
| 摘要 |
<p>The present invention provides a combined therapy for treating loss of GABA-mediated pre-synaptic inhibition after spinal injury. The therapeutic regimen includes spinal segment-specific upregulation of GAD65 (glutamate decarboxylase) gene and administration of a GABA uptake inhibitor to modulate chronic spasticity in patients after spinal traumatic or ischemic injury.</p> |
| 申请公布号 |
CA2898617(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
CA20142898617 |
申请日期 |
2014.01.22 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MARSALA, MARTIN |
| 分类号 |
A61K31/197;A61K48/00;A61P25/00 |
主分类号 |
A61K31/197 |
| 代理机构 |
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代理人 |
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