发明名称 Anticuerpos específicos para trop-2 y sus usos
摘要 The present invention provides antibodies that specifically bind to trophoblast cell-surface antigen-2 (Trop-2). The invention further provides antibody conjugates comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and Trop-2 antibody conjugates for the treatment of a condition associated with Trop-2 expression (e.g., cancer), such as colon, esophageal, gastric, head and neck, lung, ovarian, or pancreatic cancer.
申请公布号 CO7010785(A2) 申请公布日期 2014.07.31
申请号 CO20140100190 申请日期 2014.05.09
申请人 RINAT NEUROSCIENCE CORP. 发明人 LIU SHU-HUI;HO WEI-HSIEN;STROP PAVEL;DORYWALSKA MAGDALENA GRAZYNA;RAJPAL ARVIND;SHELTON DAVID L.;TRAN THOMAS-TOAN
分类号 C07K16/30;A61K47/48 主分类号 C07K16/30
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