| 发明名称 |
METHODS OF TREATMENT USING ANTI-ERBB ANTIBODY-MAYTANSINOID CONJUGATES |
| 摘要 |
The application concerns methods of treatment using anti-ErbB receptor antibody-maytansinoid conjugates, and articles of manufacture suitable for use in such methods. In particular, the invention concerns ErbB receptor-directed cancer therapies, using anti-ErbB receptor antibody-maytansinoid conjugates. |
| 申请公布号 |
US2014212411(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
US201314032046 |
申请日期 |
2013.09.19 |
| 申请人 |
Schwall Gail Colbern;GENENTCH, INC. ;IMMUNOGEN, INC. |
发明人 |
BLATTLER Walter;SCHWALL Ralph;SLIWKOWSKI Mark;ERICKSON Sharon;CHARI Ravi V.J. |
| 分类号 |
A61K47/48;A61K31/5365;A61K39/395 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treatment of cancer that expresses ErbB2 in a mammal, the method comprising administering an anti-ErbB2 antibody-maytansinoid conjugate, wherein the anti-ErbB2 antibody is a growth inhibitory antibody that binds to ErbB2 and inhibits the growth of cancer cells overexpressing ErbB2. |
| 地址 |
US |
